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Adams-Oliver syndrome
Background
Adams Oliver syndrome: AOS; Absence Defect of Limbs, Scalp and Skull; Congenital Scalp Defects with Distal Limb Reduction Anomalies.
Since its first description in 1945, Adams-Oliver syndrome (AOS) remains a rare condition with some 130 cases reported in the medical literature to date. It is characterised by a combination of defects mainly in the formation of the scalp and/or the underlying cranium (skull) with associated abnormalities of limb development.
