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Adrenoleukodystrophy

Background

Adrenoleukodystrophy: Schilder's disease; Sudanophilic Leukodystrophy; ALD

Adrenoleukodystrophy (ALD) is a life-threatening genetic disorder in which the fatty covering of nerve fibres, the myelin sheath, is progressively damaged. Without the myelin sheath, the nerves do not work as they should. This condition also affects the adrenal gland (which is located on top of the kidneys and releases hormones). It is an X-linked disorder and therefore mainly affects males.

What are the symptoms? View What are the symptoms?

Medical text written December 2011 by Dr Helen Mundy, Consultant in Paediatric Inherited Metabolic Disease, Evelina Children's Hospital, London, UK.

 

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