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Albright Hereditary Osteodystrophy
Background
Albright Hereditary Osteodystrophy (AHO) is a genetic condition characterised by a wide range of features. These include short stature in adulthood, a tendency for obesity and brachydactyly (shortening of the bones in the hands and feet). Other features may include a rounded face, wide neck and small subcutaneous ossifications (hard lumps under the skin). Some individuals with AHO have delayed learning skills. The range and severity of symptoms varies from one person to another. The height and weight of individuals with AHO can be normal, particularly in childhood.
There are two types of AHO. These are 'AHO with Pseudo Hypoparathyroidism' (PHP) and 'AHO with Pseudo Pseudo Hypoparathyroidism' (PPHP). Both types have the same cause and both types can occur within the same family.
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