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Anophthalmia
Background
Anophthalmia is a rare congenital (present at birth) abnormality in which a baby has no eye in the socket. If the eye is small, this is called microphthalmia. Anophthalmia can affect both eyes, causing blindness, or just one eye. The other eye may have less severe eye development anomalies, such as microphthalmia, cataract, corneal opacity or coloboma. Anophthalmia or severe microphthalmia occurs in 19 in 100,000 live births.