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Coloboma
Background
Coloboma is the term used to describe a gap or cleft in one of the structures of the eye. It occurs in the early stages of pregnancy when a part of the eye fails to complete its growth and fuse together leaving a gap. It does not mean that there is a hole in the eye. Different parts of the eye may be affected, including the lens, choroid, retina, optic nerve, and most commonly the iris, resulting in a ‘keyhole-shaped’ pupil.