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Holt-Oram syndrome

Background

Holt-Oram syndrome is the name given to the association of heart defect and upper limb abnormality first described by Dr Mary Holt and Dr Samuel Oram in 1960. Since then over a hundred cases have been reported worldwide. 

What are the symptoms? View What are the symptoms?

Medical text written May 1995 by Dr R Newbury-Ecob. Last updated December 2005 by Dr R Newbury-Ecob, Consultant in Clinical Genetics, Clinical Genetics Service, St Michael's Hospital, Bristol, UK.

 

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