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Isodicentric 15

Background

Isodicentric 15: idic (15)

Isodicentric 15 (idic 15) is a rare chromosomal disorder (see the chromosome abnormalities section in Patterns of Inheritance). Individuals with idic (15) have an extra chromosome made up of some material from the fifteenth pair of chromosomes. This means that there are 47 chromosomes (or occasionally 48 or 49) in these cells rather than 46 (the normal number in a diploid human cell). The extra piece of chromosome 15 is duplicated end-to-end like a mirror image and is referred to as an 'isodicentric 15', an 'inverted duplication 15', or a 'supernumerary marker'.

What are the symptoms? View What are the symptoms?

Medical text written February 2002 by Contact a Family. Approved February 2002 by Dr N Dennis, Senior Lecturer in Clinical Genetics and Honorary Consultant Clinical Geneticist, Princess Anne Hospital, Southampton, UK. Last updated February 2010 by Dr Alan Fryer, Consultant Clinical Geneticist, Royal Liverpool Children’s Hospital, Liverpool, UK.

 

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