Larsen syndrome
Background
Larsen syndrome was first described in 1950 by an orthopaedic surgeon, Joseph Larsen. He noticed that a number of his patients shared common features including multiple dislocations of the major joints (wrists, elbows, hips and knees), deformities of the feet and an unusual facial appearance characterised by a flat nasal bridge, wide-spaced eyes, and a prominent forehead.