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Leber's Congenital Amaurosis
Background
Leber's Congenital Amaurosis: Leber's Amaurosis; LCA
Leber's congenital amaurosis (LCA) is a rare, inherited retinal disorder in which there is poor vision, nystagmus (involuntary side to side movements of the eyes) and evidence of abnormal retinal function from infancy. LCA is not a single disorder as the same signs of the condition may be seen with faults in at least ten different genes and more causative genes remain to be discovered. What is common to all forms of LCA is that the photoreceptors (the light-sensitive cells in the retina) do not function normally.