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Leigh syndrome
Background
Leigh syndrome: Leigh's disease; Leigh's Encephalopathy
This is a disease that affects the brain and gets worse over time. Most patients start having problems by the age of two years, deteriorate rapidly and, sadly, many die within a year or two. Typically, there is a ‘step-wise’ downhill course: patients may deteriorate rapidly and then show partial recovery over a few weeks, followed by periods in which their condition is stable. Other patients have their first problems later in childhood and these patients often survive into adulthood.