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  MENINGITIS  

Meningitis is a condition in which inflammation of the meninges (lining) of the brain and spinal cord occurs due to a bacterial, viral or, rarely, fungal infection. The bacterial form is life threatening. Fungal meningitis also tends to be severe while the viral form is usually less so. Bacterial meningitis can be caused by many different bacteria including meningococcus, Haemophilus influenzae type b (Hib), pneumococcus, leptospirosis (including Weil's disease), tuberculosis, listeria, streptococcus and E.coli. The organisms affecting the newborn baby are often different from those affecting the older child or adult and the outcome is more serious.

Viral meningitis is commonly caused by the coxsackie and ECHO viruses. Some viruses cause a combination of meningitis and encephalitis i.e. meningoencephalitis. Mumps meningoencephalitis was common, but no longer so, because of the widespread use of the MMR vaccine.

Children and adults with particular diseases, such as those of the immune system, including HIV infection, may be more susceptible to some forms of bacterial or fungal meningitis.

Complications of meningitis include deafness (which may be total), brain damage, cerebral palsy, epilepsy and changes in eyesight. Behavioural changes such as subsequent temper tantrums, aggression and mood swings may also cause problems. Meningococcal disease, which involves blood poisoning, may cause the loss of fingers, toes and sometimes even part of a limb.

Prevention in the form of safe and effective vaccines against some forms of meningitis are now available. A primary course of conjugate Hib, meningococcal C and pneumococcal vaccines is given between eight and sixteen weeks of age. Boosters are given at twelve and thirteen months. Mumps vaccine is part of the MMR vaccine, the first of two doses being given at thirteen months old. BCG vaccine against tuberculosis is offered to all children and babies who are felt to be at higher risk.

Inheritance patterns
Usually none. Very rarely a tendency to meningococcal disease may run in families. Tests are available to check on this, where appropriate.

Prenatal diagnosis
None

Medical text written February 2001 by Dr D Elliman and Dr H Bedford. Last updated October 2006 by Dr D Elliman, Consultant in Community Child health, Islington Primary Care Trust, London, UK and Great Ormond Street hospital, London, UK and immunisation Co-ordinator, Islington Primary Care Trust and Dr h Bedford, Senior lecturer, Centre for Paediatric Epidemiology and Biostatistics, institute of Child health, London, UK.

Further information can be found by referring to the Immunisation page and the Health Promotion, England Web: http://www.immunisation.org.uk

MENINGITIS TRUST

Meningitis Trust Fern House
Bath Road
Stroud
GL5 3TJ
Tel: 0800 028 1828 Freephone Nurse-lead Helpline (24 hours)
Tel: 01453 768003 Minicom
Fax: 01453 768001
e-mail: info@meningitis-trust.org
Web: http://www.meningitis-trust.org
Web: http://www.inmed.co.uk (for health professionals)
Web: http://www.meningitis-schools.org (resources for teachers of children 14-16 years)

The Trust is a National Registered Charity No. 803016, established in 1986. It aims to ensure that affected people receiving quality care and support for life and is working towards the eradication of menintitis and meningococcal septicaemia (blood poisoning). It offers a range of services to affected people, professionals and the general public. The Trust provides professional counselling, home visiting and financial grants. It raises awareness of Meningitis throught education, training and research.

Group details last confirmed Spetember 2007.

MENINGITIS RESEARCH FOUNDATION

Meningitis Research Foundation
Midland Way
Thornbury
Bristol
BS35 2BS
Tel: 080 8800 3344 (24-hour helpline)
Tel: 01454 281811
Fax: 01454 281094
e-mail: info@meningitis.org
Web: http://www.meningitis.org

The Foundation is a National Registered Charity No. 328205, established in 1989. It offers information, befriending and support for people affected by Meningitis and funds scientific research into the prevention, detection and treatment of meningitis and septicaemia, the blood poisoning form of Meningitis. It publishes a quarterly newsletter 'Microscope' and has a wide range of information available, details on request. The Foundation has 5,000 members in the UK and Republic of Ireland.

Group details last confirmed March 2007.