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Muscular Dystrophy and Neuromuscular disorders

Background

The muscular dystrophies are a group of disorders caused by a genetic abnormality, that results in progressive weakness. Although genetic in origin, there are various reasons why an affected individual might have no family history of a similar condition. Some of the muscular dystrophies are severe and limit life expectancy, others relatively mild.

Muscular dystrophies belong to a broader group of conditions called neuromuscular disorders. These are defined as conditions affecting the nerves which pass from the brain and spinal cord to the muscles, for example spinal muscular atrophy and peripheral neuropathy, the muscles themselves, and the complex junction between each nerve and muscle (myasthenic conditions). Most neuromuscular disorders cause weakness and it can be very difficult for even a specialist to identify the precise cause of the problem. Many, but not all, neuromuscular disorders are inherited. Accurate diagnosis is essential in order to offer the appropriate management and genetic advice.

Muscular dystrophies and neuromuscular disorders View Muscular dystrophies and neuromuscular disorders

Medical text written September 2001 by Dr D Hilton-Jones. Last updated December 2005 by Contact a Family. Approved December 2005 by Dr D Hilton-Jones, Clinical Director, Department of Clinical Neurology, University of Oxford, Oxford, UK.

 

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