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Necrotising Fasciitis

Background

Necrotising Fasciitis is a rare, but serious soft tissue infection involving the skin, subcutaneous tissue and muscle.

There are several recognised risk factors. Patients who have compromised immunity such as patients with diabetes mellitus, cancer, peripheral vascular disease, intravenous drug users, those who have recently undergone surgery, receiving steroids or other immunosuppressive treatments are all predisposed. Healthy children whose skin is breached by minor trauma or skin infection are also at increased risk. In particular, children with recent Varicella Zoster virus infection (chicken pox) are prone and some investigators have suggested that the use of nonsteroidal anti-inflammatory drugs in these children increase the risk of necrotising fasciitis. Since the mid 1980's the number of cases have been increasing in healthy individuals with little or no compromise to their immunity or skin integrity.

What are the symptoms? View What are the symptoms?

Medical text written August 2002 by Dr P Salt, Registrar, Paediatric Intensive Care Unit, St Mary's Hospital, London, UK.

 

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