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Pelizaeus-Merzbacher disease

Background

Pelizaeus-Merzbacher disease: PMD

Pelizaeus-Merzbacher disease (PMD) is a neurological disorder and involves the deficiency and loss myelin (the white matter of the brain). Children with PMD display seriously affected development. PMD was described more than 100 years ago and a number of different types have been described since.

What are the symptoms? View What are the symptoms?

Medical text written April 2002 by Professor S Malcolm, Head of the Department of Molecular Genetics, Institute of Child Health, London, UK. Last updated February 2010 by Professor Brian Neville, Emeritus Professor of Paediatric Neurology, UCL Institute of Child Health and Great Ormond Street Hospital, London, UK.

 

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