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Proteus syndrome
Background
Proteus syndrome is a rare disorder named after the Greek god Proteus, ‘the polymorphous’, who could change shape at will to avoid capture. The name reflects the highly variable presentation of this disorder. Wiedemann and colleagues in 1983 who named it were unaware that this syndrome had already been described. Cohen and Hayden in 1979 published ‘a newly recognised hamartomatous syndrome’. Joseph Carey Merrick, the ‘Elephant Man’, probably had the most severe form of Proteus syndrome. To date, more than 150 cases have been reported.
