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Smith-Magenis syndrome
Background
Smith-Magenis syndrome (SMS) is a rare condition that is associated with developmental delay, learning difficulties (see entry Learning Disability), behavioural difficulties and a disturbed sleep pattern. SMS was first described by Ann Smith and colleagues in 1982. At least 1 in 25,000 children are born with this condition, and it is probably under diagnosed. Recent estimates suggest the number could be nearer to 1 in 15,000.