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Triple-X syndrome

Background

Triple-X syndrome is a chromosomal condition which occurs only in females. A chromosome is a rod-like structure present in the nucleus of all cells in the body, with the exception of the red blood cells, which stores genetic information. Normally humans have 23 pairs of chromosomes, 46 chromosomes in total. The 23 pair, otherwise referred to as the sex chromosomes, stores genetic information which determines our sex. A male has a XY pair and a female has a XX pair of chromosomes.

A female affected by triple-X syndrome has an XX pair of chromosomes, as well as additional X chromosome, resulting in the formation of XXX. A mosaic form also occurs where only a percentage of body cells contain XXX while the remainder carry XX. The extent to which an individual is affected by the condition will depend upon the proportion of XXX to XX throughout the body's cells.

What are the symptoms? View What are the symptoms?

Medical text written August 2002 by Contact a Family. Approved August 2002 by Dr R Stanhope. Last reviewed February 2008 by Dr R Stanhope, Consultant Paediatric Endocrinologist, The Portland Hospital, London, UK.

 

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