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Xeroderma Pigmentosum

Background

Xeroderma pigmentosum (XP) is a group of rare inherited conditions that is characterised by defective repair of DNA damaged by ultraviolet light, particularly from the sun. There are at least eight different subtypes recognised, which are referred to as complementation groups A to G and XP variant. Each subtype has a different genetic abnormality and capacity to repair DNA. The subtypes show different degrees of severity.

What are the symptoms? View What are the symptoms?

Medical text written December 1999 by Dr J Reed, Specialist Registrar, Department of Dermatology, Amersham Hospital, Amersham UK. Last updated July 2004 by Dr. Sheru George, Consultant Dermatologist, Amersham Hospital, Amersham ,UK.

 

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