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For many parents of disabled children it is very difficult to think about paid employment, particularly if your child needs a lot of care. This guide is aimed at parents who are thinking about returning to work or are currently in employment and includes information about what support is available and your rights at work.

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Congenital Hyperinsulinism

Background

Congenital Hyperinsulinism: Persistent Hyperinsulinaemic Hypoglycaemia of Infancy; PHHI; Nesidioblastosis (old name)

Congenital Hyperinsulinism (CH) is a rare inherited disorder in which the regulation of the secretion of insulin is faulty and there is an over production of insulin from the beta cell of the pancreas. Insulin is the most important hormone that controls the blood glucose (sugar) level. Too much insulin leads to hypoglycaemia (low blood glucose levels). If the hypoglycaemia is not treated it can cause brain damage, learning disability and even death. It is thought that CH occurs in about 1 in 40,000 live births with a male to female ratio of 1.3 to 1. Neonatal onset CH shows in the first days or weeks after birth and is the most severe form. Infant onset CH shows in the first few months, or even years, of life and is milder. A rare adult onset form of CH has been documented. CH occurs in all ethnic groups.

What are the symptoms? View What are the symptoms?

Medical text written December 2005 by Contact a Family. Approved December 2005 by Dr K Hussain, Consultant Paediatric Endocrinologist, Great Ormond Street Hospital and Institute of Child Health, London, UK.

 

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