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Cystic Fibrosis

Research

Survival steadily increases (now around 37 years) and will continue to do so due advances in the present conventional treatment most of which has been developed at CF centres. However, since the identification of the Cystic Fibrosis gene in 1989 much research has been directed at correcting the effects of the basic genetic defect either by rescuing the function of the faulty gene product (CFTR) by various drugs or by replacing the defective genetic material – so-called gene replacement therapy. Progress in both these areas is proceeding rapidly and more effective treatment for the basic defect is a real possibility within the next 5 to 10 years.

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Medical text written June 2008 by Dr J Littlewood, Chairman of the Cystic Fibrosis Trust Research and Medical Advisory Committee, Bromley, UK.

 

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