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Glanzmann's Thrombasthenia

What are the causes?

In patients with GT a particular protein (called IIb IIIa) is either missing from the platelets or does not work properly. The result is that the platelets cannot stick together adequately to form the haemostatic plug and bleeding is not stopped even from minor injuries. The number of platelets in the blood is normal and specialised tests are required to make the diagnosis.

View What are the symptoms? What are the symptoms?  |  How is it treated? View How is it treated?

Medical text (paediatric) written August 2001 by Dr R F Stevens, Consultant Haematologist/Oncologist, Royal Manchester Children's Hospital, Manchester, UK and (adult) November 2002 by Dr M Laffan. Last reviewed October 2005 by Dr M Laffan, Reader in Haemostasis and Thrombosis & Honorary Consultant in Haematology, Imperial College School of Medicine, London, UK.

 

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