|
|
|
|
||||
Hypomelanosis of Ito
Inheritance patterns and prenatal diagnosis
Inheritance patterns
This is not an inherited disorder since the error occurs after conception in one population of cells. Reports in older literature of familial cases are unconvincing. It is believed to be due to chromosomal mosaicism and sporadic gene changes. The specific gene(s) involved has not been confirmed. Pigmentary mosaicism should be differentiated from the X-linked condition of Incontinentia Pigmenti where the areas of increased pigment are preceded by blistering skin lesions.
Prenatal diagnosis
This condition is not recurrent. Management in future pregnancies should be routine, although detailed scanning may provide added reassurance.
What are the causes?
| Is there support? 
Donate Now
makingcontact.org
Pounds for parents
Subscribe to the 