Joubert syndrome
What are the causes?
Joubert syndrome is caused by changes in a gene on chromosome 9. These changes affect development of certain parts of the brain including the cerebellar vermis and brain stem. The cerebellar vermis is responsible for controlling posture, co-ordinating head and eye movements and fine-tuning muscles. The brain stem is responsible for maintaining the body's involuntary functions such as heartbeat, breathing, and thermoregulation. The cerebellar vermis and brain stem are underdeveloped or absent in individuals with Joubert syndrome. Such changes may be identified on an MRI scan of the brain.
What are the symptoms?
| How is it treated? ![]()