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Li-Fraumeni syndrome

How is it treated?

Treatment in LFS is determined by the type of cancer involved and may include surgery, chemotherapy or radiotherapy. However, radiotherapy and screening using x-rays should be avoided if possible. Urgent TP53 mutation screening is indicated for young onset breast cancer at under thirty in individuals in families with LFL or for breast cancer usually at under forty for those in a family known to be affected by classical LFS. This screening will help to determine if surgery rather than radiotherapy should be used in the breast cancer treatment.

View How is it diagnosed? How is it diagnosed?  |  Inheritance patterns and prenatal diagnosis View Inheritance patterns and prenatal diagnosis

Medical text written October 2004 by Contact a Family. Approved October 2004 by Dr R Eeles, Reader in Clinical Cancer Genetics and Hon. Consultant in Cancer Genetics and Clinical Oncology, Institute of Cancer Research, Royal Marsden NHS Trust, Sutton, UK.

 

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