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Moya Moya disease

What are the causes?

Although the direct cause of Moya Moya is often uncertain it can be seen in a number of diseases that can affect arteries: Trisomy 21 (Down syndrome), Sickle Cell disorders, chronic Meningitis and Neurofibromatosis.

The internal carotid artery is one of the major arteries to the brain. This artery branches into many smaller vessels in order to reach all areas of the brain. In patients with Moya Moya, there is narrowing of the internal carotid arteries and their major branches which reduces the blood supply to the brain. The brain responds by increasing the size of many smaller vessels to improve blood flow to deprived areas of the brain. In children, the first symptom is often stroke, which may cause paralysis of one side of the body or sometimes seizures. In some children development slows down or skills may be lost. Adults are more prone to acute bleeding in the head.

View What are the symptoms? What are the symptoms?  |  How is it diagnosed? View How is it diagnosed?

Medical text written October 2006 by Contact a Family and Professor Brian Neville, Professor of Childhood Epilepsy, Institute of Child Health/Great Ormond Street Hospital, London, UK.

 

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