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Multiple Endocrine Neoplasia Type I

What are the causes?

MEN I occurs where two or more of the following endocrine glands develop tumours (hyperplasia or adenoma); the pancreas which is located behind the stomach; the parathyroid gland which is located in the neck; and the pituitary gland which is located in the head. Normally, hormones are secreted by endocrine glands in a carefully balanced way to regulate specific body functions and meet the body's needs. The presence of tumours in MEN I results in the over-production of hormones and this is associated with a range of medical problems. Over-activity of more than one endocrine gland may occur at the same time or later on in a person's life.

View What are the symptoms? What are the symptoms?  |  Inheritance patterns and prenatal diagnosis View Inheritance patterns and prenatal diagnosis

Medical text written September 2003 by Contact a Family. Approved September 2003 by Professor R V Thakker. Last updated January 2006 by Professor R V Thakkar, Head of the Molecular Endocrinology Group, John Radcliffe Hospital, Oxford, UK.

 

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