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Multiple Endocrine Neoplasia Type II

Inheritance patterns and prenatal diagnosis

Inheritance patterns
All MEN II subtypes are inherited as an autosomal dominant trait. Changes in a gene on chromosome 10 (known as RET) are associated with the clinical features. Genetic testing is available in individuals who are unaffected with MEN II. Genetic counselling is advised for all individuals and families prior to genetic testing.

Prenatal diagnosis
This may be possible. Genetic counselling is advised for all individuals and families prior to genetic testing together with further specialist information and support.

View What are the symptoms? What are the symptoms?  |  Is there support? View Is there support?

Medical text written September 2003 by Contact a Family. Approved September 2003 by Professor R V Thakker. Last updated January 2006 by Professor R V Thakkar, Head of the Molecular Endocrinology Group, John Radcliffe Hospital, Oxford, UK.

 

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