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Ohdo syndrome
What are the symptoms?
Affected children are often very floppy at birth and have major feeding problems requiring tube feeding. They have generally decreased movements, particularly facial movements. Some, but not all, children have heart problems and some have an absent part of the brain called the corpus callosum. When the teeth erupt they are often very small. Many older children have had joint problems ranging from mild bending of a finger to more severe hip disorders.
Progress in the first year of life is slow, and head control, sitting and walking occur late. However, ultimate progress is often better than was anticipated at first although all children have mild to moderate learning difficulties. Some children do not survive, due to the severity of their heart defects or to major respiratory problems.
Background
| Inheritance patterns and prenatal diagnosis 
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