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Osteoporosis (Adult)

What are the cause?

Osteoporosis affects 1 in 2 women and 1 in 5 men during their lifetime. Bone loss occurs as individuals get older with increased incidence seen as life expectation in the population increases. There are also many other factors which can increase the risk of osteoporosis:

For women:

a lack of oestrogen, caused by

  • early menopause (before the age of 45)
  • early hysterectomy (before the age of 45), particularly when both ovaries are removed (oophorectomy)
  • missing periods for six months or more (excluding pregnancy) as a result of over-exercising or over-dieting

For men:

  • low levels of the male hormone, testosterone (hypogonadism)

For men and women:

  • long-term use of high dose corticosteroid tablets (for conditions such as arthritis and asthma)
  • close family history of osteoporosis (mother or father), particularly if an individual's mother has suffered a hip fracture
  • other medical conditions such as Cushing's syndrome, intestinal diseases and liver and thyroid problems
  • malabsorption problems (Coeliac disease, Crohn's disease, gastric surgery)
  • long-term immobility
  • heavy drinking
  • smoking

The presence of one or more of these factors puts an individual at increased risk of developing osteoporosis. Such individuals should discuss prevention and treatment with their doctor.

View Background Background  |  How is it treated? View How is it treated?

Medical text written November 2000 by the National Osteoporosis Society. Approved November 2000 by Professor Anthony Woolf, Consultant Rheumatologist, Royal Cornwall Hospital, Truro UK. Last updated May 2005 by Professor D M Reid, Professor of Rheumatology, University of Aberdeen Medical School, Aberdeen, UK.

 

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