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Porencephaly

What are the causes?

The aetiology, in children, is thought to be that there is a localised destruction of brain tissue due to a number of causes but potentially including toxaemia, maternal injuries, infection, hypoxic injury or even intra-uterine intra-cerebral haemorrhage. It has been seen after multiple taps of the ventricles (fluid cavities inside the brain) to relieve raised intracranial pressure. Its overall incidence is unknown, aetiology must be multi-factorial and some series suggest that there is a risk that a patient with porencephaly has a two to four per cent chance of having a child with a neural tube defect.

People with mature brains can get similar cysts developing due to loss of brain tissue after brain haemorrhages, strokes, head injuries, etc. These cysts, like porencephalic cysts, are what is left behind by the normal process of the brain clearing away dead tissue as part of the normal healing processes of the body.

View Background Background  |  How is it treated? View How is it treated?

Medical text written February 2003 by Mr N Buxton. Last Updated July 2008 by Mr N Buxton, Consultant Paediatric Neurosurgeon, Alder Hey Children's Hospital, Liverpool, UK.

 

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