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Progressive Supranuclear Palsy

What are the symptoms?

PSP is a very individual disease and can present in different ways making diagnosis very difficult, particularly early in the disease. In the early stages, symptoms can include loss of balance and unexpected falls, often backwards, and difficulties with vision, particularly in upgaze and downgaze. Bright lights can be painful and the patient often presents with a characteristic 'Mona Lisa' type stare. Difficulty in walking, with a resulting broad-based unsteady shuffling gait can be observed in many cases. As the disease progresses, slurring of speech with a growly, guttural tone, together with increasing problems in swallowing can be noticed. These problems can also lead to loss of communication ability and the need for a gastrostomy for tube feeding. Other symptoms, may include dry eyes, stiff neck and incontinence.

View Background Background  |  How is it treated? View How is it treated?

Medical text written October 2000 by Professor A J Lees. Last reviewed January 2005 by Professor A J Lees, Consultant Neurologist, The National Hospital for Neurology, London, UK and Director of Research, Reta Lila Weston Institute of Neurological Studies, London, UK and Chairman of the PSP Association Medical Advisory Panel.

 

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